Near‐Infrared and Visible Dual‐Emitting Peptide by Modular Assembly of Nitrobenzoxadiazole and Neodymium Complexes - Département Recherches Subatomiques
Journal Articles Advanced Optical Materials Year : 2024

Near‐Infrared and Visible Dual‐Emitting Peptide by Modular Assembly of Nitrobenzoxadiazole and Neodymium Complexes

Wanqi Zhou
Kaitlin Hao‐yi Chan
Waygen Thor
Fan Zhang
Yong Fan
Yue Wu

Abstract

The synthetic difficulty of target‐specific lanthanide complexes, despite their unique characteristics, limits their use in in vitro/ in vivo studies and biomedical applications. With commercially available and affordable reagents, a facile synthetic approach is developed to modularly deploy nitrobenzoxadiazole and neodymium complexes onto bioactive peptides. The yielded probes show observable neodymium emission with specific localization to corresponding biotargets in vitro, which became the first example of a stable, water‐soluble, and target‐specific neodymium(III) complex applicable for in vitro imaging with detectable brightness.
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Origin Publication funded by an institution

Dates and versions

hal-04750052 , version 1 (05-11-2024)

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Yik‐hoi Yeung, Ho‐fai Chau, Hei‐yui Kai, Wanqi Zhou, Kaitlin Hao‐yi Chan, et al.. Near‐Infrared and Visible Dual‐Emitting Peptide by Modular Assembly of Nitrobenzoxadiazole and Neodymium Complexes. Advanced Optical Materials, 2024, 12 (9), pp.2302070. ⟨10.1002/adom.202302070⟩. ⟨hal-04750052⟩
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