Psychological distress is a common phenomenon that can be seen in students, and particularly university students who are exposed to high levels of stress at university due to the large and new responsibilities or challenges related to this period. The aim of this study is to expose the feasibility of Internet-based stress management intervention for response of the problem above. The present study was led by an Internet-based stress management intervention composed of four sessions and by a battery of self-report questionnaires online, including four questionnaires: Perceived Stress Scale (PSS-10), Rosenberg Self-Esteem Scale (RSES), Satisfaction with Studies Scale (ESDE); General Health Questionnaire (GHQ-28), during the " pre-intervention " and the " post-intervention " stages. Our results have shown that the stress levels and well-being are improvable according to time (pre/post intervention). Specifically , the results showed that effect sizes is small effects for Self-esteem, Satisfaction in studies and Psychological distress; medium effects for two sub-factors of GHQ-28 Anxiety/insomnia and Social dysfunction; large effects for PSS-10(Perceived Stress) and his sub-factors: Perceived helplessness and Perceived self-efficacy. Despite of many advantages, this type of intervention on stress management has its limits and a major methodological problem, which is the high attrition rate.